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giant cell : ウィキペディア英語版
giant cell

A giant cell is a mass formed by the union of several distinct cells (usually macrophages), often forming a granuloma. It can arise in response to an infection, such as from tuberculosis, herpes, or HIV, or foreign body. These multinucleate giant cells also known as (MGCs) are cells of monocyte or macrophage lineage fused together.
Types include:
* foreign-body giant cell
* Langhans giant cell
* Touton giant cells
* giant-cell arteritis
* Reed–Sternberg cell
Also
* as in subependymal giant cell astrocytoma
==History==
Multinucleated giant cell formations can arise from numerous types of bacteria, diseases, and cell formations. Giant cells are known to develop when infections are also present. They were first noticed as early as the middle of the last century, but still it is not fully understood why these reactions occur. In the process of giant cell formation, monocytes or macrophages fuse together, which could cause multiple problems for the immune system.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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